Ondansetron Injection also known as a Zofran, this drug is commonly used to help treat nausea and vomiting in humans, but can also be prescribed for off-label use in dogs and cats. It can be helpful for animals suffering from vomiting due to chemotherapy treatment. It s also a treatment option for pruritus (itching) and sleep apnea in some cases. Intended for intravenous or intramuscular injection only.How it Works

Ondansetron works through the inhibition of the 5HT3 serotonin receptors. These particular receptors are part of vagal nerve terminals and enteric neurons located in the GI tract. They are also located in the chemoreceptor trigger zone of the brain.

Special Precautions

Keep away from children and animals. Ondansetron should not be used in animals with known hypersensitivity or allergy to the drug.

Overdose Information

Immediately contact your closest emergency animal hospital or vet.

Side Effects

While veterinary medicine doesn't typically use this medication, it can prove to be tolerated well. Possible side effects include:

• Sedation
• Constipation
• Arrhythmias
• Hypotension
• Head shaking (extrapyramidal clinical signs)